Paul AllenPortland Trail Blazers owner Paul Allen during the second half of an NBA basketball game against the Golden State Warriors Wednesday, Jan. 4, 2017, in Oakland, California.Marcio Jose Sanchez/AP

Paul Allen, the cofounder of Microsoft and billionaire philanthropist, died Monday afternoon after battling non-Hodgkin’s lymphoma.

The 65-year-old Seattle native is best-known for having launched Microsoft with Bill Gates, but he also operated the venture-capital firm Vulcan Ventures, and staked his claim on sports franchises as the owner of the Seattle Seahawks and Portland Trail Blazers.

Allen previously overcame a bout of Hodgkin’s lymphoma in the 1980s, but he was later diagnosed with cancer in 2009, which returned after a period of remission.

As a titan in the tech industry and the world of sports, Allen influenced his colleagues to inspire millions of others through their work.

Here’s how Allen’s friends and associates are responding to his death.